Role of heritable connective tissue diseases phenotypes in assessing the risk for internal diseases

Connective tissue diseases.

Undiagnosed connective tissue diseases

Among different subgroups of pulmonary arterial hypertension (PAH), those associated with connective tissue diseases (CTDs) have distinct hemodynamic and prognostic features; a correct etiologic diagnosis is thus mandatory.To estimate frequency and prognosis of previously undiagnosed CTDs in a suspect idiopathic (i) PAH cohort.Consecutive patients with PAH confirmed by right heart catheterizati...

The real connective tissue diseases.

689–90. 16 Corrao S, Salli L, Arnone S, Scaglione L, et al. Echodoppler abnormalities in patients with rheumatoid arthritis without clinically evident cardiovascular disease. Eur J Clin Invest 1996;26:293–7. 17 Slack D, Waller B. Acute congestive heart failure due to the arteritis of rheumatoid arthritis. Early diagnosis by endomyocardial biopsy. Angiology 1986;6:477–81. 18 Banks MJ, Flint EJ, ...

The role of adipokines in connective tissue diseases

OBJECTIVE To discuss the relationship between adipokines and connective tissue diseases, by putting special emphasis on the potential role of leptin, adiponectin, resistin, and other adipose tissue products in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus and on possible application of adipokine-targeted therapy in the treatment of these disorders with emphasis on th...

Risk factors for coronary heart disease in connective tissue diseases.

Atherosclerosis and cardiovascular disease risk is enhanced in certain connective tissue diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic vasculitis and antiphospholipid syndrome. The reason for this accelerated process is likely to be multifactorial. Traditional risk factors are more prevalent in some of these patient groups compared with the general pop...